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Main Sequence Ventures — Portfolio

Investor actively backing innovative startups and growth-stage companies across various industries and funding rounds.

98
Companies
$1.8B
Total invested
$18.8M
Avg. check
54
Industries
Biotechnology 5Artificial Intelligence (AI) 5Computer 4Information Technology 4Manufacturing 4Renewable Energy 4+48 more
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Portfolio companies

Showing 1–24 of 98
Universal Quantum
October 2026

Universal Quantum develops utility-scale quantum computers designed to address complex computational challenges.

Computer · Brighton$100.0M Series A
Kinoxis Therapeutics
September 2026

Kinoxis Therapeutics is a biotechnology company that develops a range of novel therapeutic compounds.

Biotechnology · Melbourne$4.8M Venture - Series Unknown
Amber Electric
September 2026

Amber Electric provides electricity plans based on wholesale energy prices with usage charges linked to market rates.

Artificial Intelligence (AI) · Melbourne$55.9M Series E
Metacognition
September 2026

Metacognition is an AI company dedicated to building the next generation of intelligent AI agents and robotic software platforms.

Agentic AI · Adelaide$7.2M Pre-Seed
Facet Amtech
August 2026

Facet Amtech develops and produces ammonia from water and air.

Chemical · Wickham$2.2M Seed
Emesent
July 2026

Emesent is automating the collection and analysis of valuable data in underground environments.

Aerospace · Pullen Vale$10.4M Convertible Note
Number 8 bio
June 2026

Number 8 bio objective is to decarbonize agriculture while feeding the world's rising population.

Agriculture · Sydney$15K Grant
Diraq
May 2026

Diraq develops quantum computers utilizing modified silicon transistors, making them suitable for utility-scale applications.

Computer · Sydney$38.0M Grant
Arkeus
May 2026

Arkeus develops AI-powered sensing and surveillance systems designed for autonomous platforms.

Artificial Intelligence (AI) · Port Melbourne$17.9M Series A
DeteQt
April 2026

Pioneers quantum magnetometry for navigation, mining, and medical imaging solutions

Information Technology · Sydney$3.5M Seed
ULUU
April 2026

ULUU is an ocean material that replaces plastic and actively benefits the world.

Advanced Materials · Perth$1.5M Grant
Cauldron Ferm
March 2026

Cauldron Ferm is a bio-acceleration process that exponentially scales up any precision fermented prototype to commercial quantities.

Biotechnology · Orange$13.3M Series A
Advanced Navigation
March 2026

Advanced Navigation creates AI-powered navigation systems and robotics technologies for use in the air, land, sea, and space.

Artificial Intelligence (AI) · Sydney$111.9M Series C
MGA Thermal
March 2026

Making 24/7 renewables a reality through Thermal Energy Storage.

Energy · Newcastle$12.0M Series Unknown
Gilmour Space Technologies
January 2026

Gilmour Space Technologies is a space rocket company that develops low-cost hybrid launch vehicles.

Aerospace · Pimpama$145.9M Series E
Kasada
December 2025

Kasada protects online, mobile, and API channels from system takeover, content scraping, DOS, and account takeover.

Computer · Sydney$19.9M Venture - Series Unknown
Sundrive Solar
November 2025

Sundrive Solar is a solar technology start-up.

Renewable Energy · Kurnell$16.5M Grant
The EVERY Company
November 2025

The EVERY Company creates and sells animal-free egg protein ingredients using a precision fermentation process.

Biotechnology · South San Francisco$55.0M Series D
Morse Micro
September 2025

Morse Micro develops Wi-Fi HaLow chips that provide secure wireless connectivity for IoT devices.

Internet of Things · Surry Hills$58.0M Series C
Endua
September 2025

Endua is developing the next generation of renewable energy multi-day storage solutions.

Energy Storage · Brisbane$20K Grant
v2food
July 2025

v2food is a leading plant-based meat company.

Alternative Protein · Sydney$16.6M Venture - Series Unknown
Levur
May 2025

Levur is a Biotechnology Research oriented firm that manufactures cosmetic oil substitutes for their customers.

Biopharma · Sydney$780K Pre-Seed
QuintessenceLabs
April 2025

QuintessenceLabs provides data security technology, products, and solutions to protect sensitive digital data.

Computer · Canberra$12.7M Venture - Series Unknown
Regrow Ag
March 2025

Regrow is an agritech company that promotes regenerative agriculture to build a climate-resilient global food production system.

Agriculture · DurhamVenture - Series Unknown

Where Main Sequence Ventures invests

Biotechnology5
Artificial Intelligence (AI)5
Computer4
Information Technology4
Manufacturing4
Renewable Energy4

About Main Sequence Ventures's portfolio

How many companies has Main Sequence Ventures invested in?▸

Main Sequence Ventures has invested in 98 companies tracked in our database. The portfolio spans multiple industries and funding stages, from seed-stage startups to late-stage companies.

What industries does Main Sequence Ventures invest in?▸

Main Sequence Ventures's top investment sectors include Biotechnology, Artificial Intelligence (AI), Computer, Information Technology, Manufacturing. The firm invests across 54 different industry categories.

What is Main Sequence Ventures's largest investment?▸

Among tracked funding rounds, Gilmour Space Technologies received $145.9M in a Series E round. Main Sequence Ventures's total known invested capital is $1.8B.

What is the average investment size for Main Sequence Ventures?▸

Main Sequence Ventures's average investment size is $18.8M across its portfolio of 98 companies.

What are Main Sequence Ventures's most recent investments?▸

Recent Main Sequence Ventures portfolio additions include Universal Quantum, Kinoxis Therapeutics, Amber Electric, Metacognition, Facet Amtech. These companies were founded in 2020 or later.

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